Julie Poitras Santos' site-specific art practice includes video, installation, and public projects that include a walking component. The relationship between site, story and mobility fuels a wide range of research and production, including the relationship between natural histories, myth and individual story; walking as a form of listening to site; and material agency in an age of climate change.

Poitras Santos’ solo and collaborative work has been exhibited at the Queens Museum, NY; Bates College Museum of Art; Center for Maine Contemporary Art; Karlskrona Konsthall in Karlskrona, Sweden, Institute for Contemporary Art at Maine College of Art; the Centre for Contemporary Culture in Barcelona, Spain; Reykjanesbaer Art Museum in Iceland; and at the Museum of Contemporary Art in Denver, among others.
In 2016, with the help of a Kindling Fund Grant through the Warhol Regional Regranting Program, Poitras Santos initiated Platform Projects/Walks, a platform for curating walking artworks within local communities.

Recent projects include co-curating with Catherine Besteman Making Migration Visible: Traces, Tracks & Pathways (2018) for the Institute of Contemporary Art at Maine College of Art. Accompanied by a state-wide initiative involving over seventy partners, and a symposium, the exhibition was supported in part by a grant from the National Endowment for the Arts.

She currently holds the position of Director of Exhibitions at the Institute of Contemporary Art at Maine College of Art, and lives in Portland, Maine.